Comprehensive Cancer Panel

Comprehensive Cancer Panel

Comprehensive Cancer Panel is a multi-biomarker NGS assay that covers the most relevant cancer genes . The panel detects relevant single nucleotide variants (SNVs), copy number variant (CNVs), gene fusions, and indels from 161 unique cancer-associated genes in single test.


Categorised by Somatic    Alteration TypeCategorised by Relevance
87  Hotspot Genes
43 Focal CNV Gains
48 Full CDS for DEL Mutations
51 Fusion Drivers
15 Genes in 66 Labels
21 Genes in 28 Guidelines
121 Genes are in >1000 Global Clinical Trials

Comprehensive Cancer Panel Gene List

AKT1
AKT2
AKT3ALKARARAFAXLBRAFBTKCBL
CCND1CDK4CDK6CHEK2CSF1RCTNNB1DDR2EGFRERBB2ERBB3
ERBB4ERCC2ESR1EZH2FGFR1FGFR2FGFR3FGFR4FLT3FOXL2
GATA2GNA11GNAQGNASH3F3AHIST1H3BHNF1AHRASIDH1IDH2
JAK1JAK2JAK3KDRKITKNSTRNKRASMAGOHMAP2K1MAP2K2
MAP2K4MAPK1MAXMDM4MED12METMTORMYCMYCNMYD88
NFE2L2NRASNTRK1NTRK2NTRK3PDGFRAPDGFRBPIK3CBPIK3CAPPP2R1A
PTPN11RAC1RAF1RETRHEBRHOAROS1SF3B1SMAD4SMO
SPOPSRCSTAT3TERTTOP1U2AF1XPO1

LEVEL 1Companion Diagnostic: Information that is essential for the safe and effective use of a corresponding therapeutics
LEVEL 2Clinically Significant: Enable health care professionals to use information about their patients’ tumours in accordance with the clinical evidence, such as professional practice guidelines
LEVEL 3Potential Clinical Significance: May be informational or used to direct patients towards clinical trials for which they may be eligible

ARID1AATMATRATRXBAP1BRCA1BRCA2CDK12CDKN1BCDKN2A
CDKN2BCHEK1CREBBPFANCAFANCD2FANCIFBXW7MLH1MRE11MSH2
MSH6NBNNF1NF2NOTCH1NOTCH2NOTCH3PALB2PIK3R1PMS2
POLEPTCH1PTENRAD50RAD51RAD51BRAD51CRAD51DRNF43RB1
SETD2SLX4SMARCA4SMARCB1STK11TP53TSC1TSC2
AKT1AKT2AKT3ALKAXLARBRAFCCND1CCND2CCND3
CCNE1CDK2CDK4CDK6EGFRERBB2ESR1FGF19FGF3FGFR1
FGFR2FGFR3FGFR4FLT3IGF1RKITKRASMDM2MDM4MET
MYCMYCLMYCNNTRK1NTRK2NTRK3PDGFRAPDGFRBPIK3CAPIK3CB
PPARGRICTORTERT
AKT2ALKARAXLBRCA1BRCA2BRAFCDKN2AEGFRERBB2
ERBB4ERGESR1ETV1ETV4ETV5FGFR1FGFR2FGFR3FGR
FLT3JAK2KRASMDM4METMYBMYBL1NF1NOTCH1NOTCH4
NRG1NTRK1NTRK2NTRK3NUTM1PDGFRAPDGFRBPIK3CAPRKACAPRKACB
PTENPPARGRAD51BRAF1RB1RELARETROS1RSPO2RSPO3
TERT