Frequently Asked Questions

01. Is NiCETM Prenatal Test the same as NIPT?


The general medical term is known as Non-Invasive Prenatal Test (NIPT).

NiCETM is the acronym for Non-invasive Chromosomal Evaluation. It is one of the genetic screening tests carried out by GenomixLab.

02. How does NiCETM Prenatal Test works? Can you determine the baby’s health and even sex by simply taking the mother’s blood?

The DNA from the baby (fetus) is present in the mother’s blood during pregnancy. A small amount of maternal blood (approximately 10mls) will be taken and the DNA from the baby will be extracted. NiCETM analyses this DNA and screen the entire 23 chromosomes including chromosome X and Y in a developing baby.

The NiCETM test report will tell you if there is a risk of having a baby with Down’s Syndrome, Edward’s Syndrome or Patau’s Syndrome with more than 99% accuracy. NiCETM will also test for sex chromosome abnormalities (chromosome abnormalities are also known as “aneuploidies”) as well as detecting the sex (gender) of your baby.

03. Can you determine the baby’s health and even sex by simply taking the mother’s blood?

The baby (or fetal) DNA circulates freely in the mother’s blood stream.

This is known as cell-free fetal DNA (cffDNA). NIPT is carried out by analysing this cffDNA and the entire 23 chromosomes including chromosomes X and Y (female and male chromosomes) can be analysed.

04. What happens if the baby’s sex (i.e. fetal sex) result from NiCETM Prenatal Test is not the same as the ultrasound results?

This is highly unlikely – however, in the event that such happens, a new maternal blood sample should be taken in a Streck tube and the GenomixLab will determine the fetal sex (free of charge).

05. What happens if the NiCETM Prenatal Test gives a positive result?

If the test indicates a positive result, your O&G Consultant will likely encourage you to do an amniocentesis or chorionic villus biopsy.

In the case of arrested pregnancy, conventional curettage is performed.

06. What are the differences with the anomalies detected by an amniocentesis?

NiCETM detects anomalies in the number of chromosomes at a chromosomal level and not in their structure. NiCETM is able to check all 23 chromosomes including detecting the gender of the fetus. It is only a screening and not a full diagnosis although for major chromosomal aneuploidies such Down’s, Edward’s and Patau’s syndromes, it is able to give more than 99% accuracy.

Your O&G Consultant would be able to let you know if you need further diagnosis test such as amniocentesis or chorionic villus sampling.

07. Can the NiCETM Prenatal Test be done with donated oocytes? And in the case of using a surrogate uterus, can it be done?

Definitely yes. The test can also be done in the case of surrogacy.

08. What about having the test in the case of twin gestations?

Yes. NiCETM Prenatal Test can be done in case of twin gestations. However, bear in mind that in such a case, we cannot provide information on the fetal sexes, or about any alterations in sexual chromosomes. The test only provides information about the presence or the absence of a Y chromosome.